Investors
May 23, 2025

If you're building an AI or machine learning startup and you're looking for venture capital funding, New York is one of the best places to start. We've compiled an updated list of the Top 40 VC firms investing heavily in AI/ML companies, along with their focus sectors, portfolio highlights, and direct contact info.
Betaworks
Location: New York, USA
Founded: 2007
Fund Type: Venture Fund / Startup Studio
Fund Stage: Seed, Series A, Series B
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Developer Tools, SaaS, Big Data & Analytics, Mobile, AR/VR, Consumer Tech, Creator Economy, IoT, FinTech
Portfolio Highlights: Hugging Face, Bubble, IFTTT, Cube Dev, Superplastic
Investments: 210
Exits: 68
Description:
Betaworks is a New York-based startup studio and venture fund known for building and investing in early-stage companies at the frontier of technology and creativity. With a strong focus on AI/ML, SaaS, developer tools, and emerging media, Betaworks backs founders reimagining the internet's next era. Their investments include notable AI pioneers like Hugging Face and experimental innovators like Bubble and IFTTT. Betaworks blends operational expertise, product acceleration, and deep community connections to help startups launch, scale, and define new categories.
Partner Contact: Josh Auerbach
Email: josh@betaworks.com
Website: www.betaworks.com
LinkedIn: Betaworks
Twitter: @betaworks
Facebook: Betaworks
Blackstone Group
Location: New York, USA
Founded: 1985
Fund Type: Corporate Venture Arm
Fund Stage: Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), CloudTech, Cybersecurity, Big Data & Analytics, Developer Tools, Enterprise Software, SaaS, Risk Management, FinTech
Portfolio Highlights: ShiftLeft, Ontra, IntSights, CyberGRX, Beacon Platform
Investments: 182
Exits: 59
Description:
Blackstone Group is one of the world’s largest investment and advisory firms, backing transformative companies across enterprise software, cybersecurity, AI/ML, and fintech. Through its corporate venture arm, Blackstone targets later-stage startups poised for market leadership. The firm brings deep operational resources, global connections, and capital strength to help scale promising technologies, including major players in AI-driven security and enterprise cloud innovation.
Partner Contact: Gregory Beutler
Email: gregory.beutler@blackstone.com
Website: www.blackstone.com
LinkedIn: Blackstone Group
Boldstart Ventures
Location: New York, USA
Founded: 2010
Fund Type: Venture Fund
Fund Stage: Seed
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, CloudTech, Developer Tools, Big Data & Analytics, Enterprise Software, Information Technology
Portfolio Highlights: Stellate, Slim.AI, Spectro Cloud, env0, FortressIQ, Reco
Investments: 157
Exits: 23
Description:
Boldstart Ventures is a New York-based seed-stage venture fund that partners with "developer-first" and SaaS founders from day one. Known for a strong emphasis on AI/ML infrastructure, enterprise cloud, and developer tools, Boldstart helps technical founders turn ambitious ideas into category-defining companies. With deep experience in early-stage scaling and a powerful founder network, Boldstart has backed innovators like Stellate, FortressIQ, and Slim.AI.
Partner Contact: Natalie Ledbetter
Email: natalie@boldstart.vc
Website: www.boldstart.vc
LinkedIn: Boldstart Ventures
Twitter: @BOLDstartVC
Facebook: Boldstart Ventures
BoxGroup
Location: New York, USA
Founded: 2009
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, B, C, D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, Developer Tools, CloudTech, Healthcare, ClimateTech, IoT, FinTech, Consumer Tech, Robotics
Portfolio Highlights: Flatiron Health, PlanetScale, Bubble, Superhuman, Capchase
Investments: 559
Exits: 103
Description:
BoxGroup is a prolific early-stage venture capital fund based in New York, backing bold founders at the earliest stages acrossSectors like AI/ML, SaaS, healthcare, and fintech. With a hands-on, founder-first approach, BoxGroup has helped launch industry-shaping startups like Flatiron Health, PlanetScale, and Superhuman. Their broad investment thesis embraces emerging technologies such as artificial intelligence, machine learning, and next-generation enterprise solutions.
Partner Contact: Nimi Katragadda
Email: nimi@boxgroup.com
Website: www.boxgroup.com
LinkedIn: BoxGroup
Twitter: @boxgroup
Facebook: BoxGroup
City Light Capital
Location: New York, USA
Founded: 2004
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Healthcare, Big Data & Analytics, Cybersecurity, IoT, ClimateTech, Productivity Tools
Portfolio Highlights: Cerebral, Xage Security, Rad AI, Rune Labs, Legends of Learning
Investments: 163
Exits: 16
Description:
City Light Capital is an early-stage venture firm that invests in mission-driven companies advancing education, safety, care, and environmental sustainability. With a strong focus on AI/ML, SaaS, healthtech, and IoT, City Light backs startups applying deep technology to solve real-world human and societal challenges. Their investments include companies like Rad AI and Xage Security, blending cutting-edge AI innovation with meaningful impact.
Partner Contact: Tom Groos
Email: tom@citylightcap.com
Website: www.citylight.vc
LinkedIn: City Light Capital
Twitter: @citylightcap
Facebook: City Light Capital
Coatue
Location: New York, USA
Founded: 1999
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, B, C, D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, FinTech, Big Data & Analytics, CloudTech, Consumer Internet, Enterprise, Developer Tools, Infrastructure, Robotics
Portfolio Highlights: Deep Instinct, Domino Data Lab, Grafana Labs, Mercury, Repl.it
Investments: 366
Exits: 38
Description:
Coatue is one of the world's leading technology investment firms, operating across public and private markets. The firm actively backs category-defining companies in AI/ML, SaaS, fintech, and enterprise software from the earliest stages through growth rounds. With an analytical, data-driven approach to investing, Coatue supports founders in scaling globally, with standout investments in AI-driven companies like Deep Instinct and Domino Data Lab.
Partner Contact: Matt Mazzeo
Email: mazzeo@coatue.com
Website: www.coatue.com
LinkedIn: Coatue Management
Contour Venture Partners
Location: New York, USA
Founded: 2005
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, Enterprise Software, FinTech, Developer Tools, CRM, RetailTech
Portfolio Highlights: SmartAsset, Wunderkind (BounceX), Slice, Movable Ink, Skopenow
Investments: 159
Exits: 24
Description:
Contour Venture Partners is a New York-based seed-stage VC fund specializing in enterprise SaaS, B2B SaaS, and financial services innovation. With an increasing focus on AI/ML-driven enterprise applications, Contour backs startups creating next-gen infrastructure in marketing tech, fintech, risk management, and data-driven business intelligence. Their portfolio includes AI-powered leaders like SmartAsset and Wunderkind, helping founders build scalable solutions from day one.
Partner Contact: Matt Gorin
Email: matt@contourventures.com
Website: www.contourventures.com
LinkedIn: Contour Venture Partners
Deerfield
Location: New York, USA
Founded: 1994
Fund Type: Venture Fund
Fund Stage: Seed, Series A, Series B
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), BioTech, Healthcare, Big Data & Analytics, Pharmaceuticals, Health & Wellness, Wearables, AgTech
Portfolio Highlights: LetsGetChecked, Frontier Medicines, TriNetX, Adaptive Phage Therapeutics, Element Science
Investments: 244
Exits: 114
Description:
Deerfield is a healthcare-focused investment management firm driving innovation at the intersection of technology and life sciences. They actively back startups applying AI/ML, big data, and predictive analytics to revolutionize healthcare, biotech, and wellnessSectors. Deerfield combines deep operational expertise, strategic partnerships, and philanthropic initiatives to help healthcare AI startups scale breakthroughs that improve patient outcomes globally.
Partner Contact: James Flynn
Email: jflynn@deerfield.com
Website: www.deerfield.com
LinkedIn: Deerfield Management
Dreamit Ventures
Location: New York, USA
Founded: 2007
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, Healthcare, SaaS, Cybersecurity, FinTech, PropTech, Developer Tools
Portfolio Highlights: EnsoData, NeuroFlow, ForMotiv, Vytalize Health, BrainCheck
Investments: 383
Exits: 43
Description:
Dreamit Ventures is a venture fund and growth platform backing startups that are ready to scale, with a sharp focus on AI/ML-driven solutions in healthcare, security, and enterprise SaaS. Dreamit helps founders validate pilots, accelerate customer acquisition, and raise follow-on capital. Their portfolio includes AI innovators like EnsoData and ForMotiv, supporting the next wave of AI/ML disruption across healthcare, cybersecurity, and enterprise software.
Partner Contact: Darren Sandberg
Email: darren@dreamit.com
Website: www.dreamit.com
LinkedIn: Dreamit Ventures
Twitter: @dreamit
Facebook: Dreamit Ventures
ff Venture Capital
Location: New York, USA
Founded: 2008
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, Cybersecurity, FinTech, IoT, Robotics, SaaS, Telecommunications
Portfolio Highlights: Plus One Robotics, Opencare, Earnest Research, JazzHR, Stocktwits
Investments: 359
Exits: 28
Description:
ff Venture Capital (ffVC) is a New York-based technology-focused venture firm that backs early-stage startups across AI/ML, cybersecurity, SaaS, and frontier techSectors like robotics and IoT. Known for providing more than capital, ffVC actively helps portfolio founders scale operations, recruit talent, and navigate early customer acquisition. They invest early in disruptive AI technologies redefining industries from enterprise software to mobility.
Partner Contact: Conor Webb
Email: conor@ffvc.com
Website: www.ffvc.com
LinkedIn: ff Venture Capital
Twitter: @ffvc
Facebook: ff Venture Capital
FirstMark Capital
Location: New York, USA
Founded: 2008
Fund Type: Venture Fund
Fund Stage: Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, Developer Tools, CloudTech, Cybersecurity, FinTech, Enterprise Software, IoT
Portfolio Highlights: ActionIQ, Crossbeam, Dashlane, Guru, Upgrade
Investments: 333
Exits: 52
Description:
FirstMark Capital is one of New York’s premier early-stage venture firms, partnering with visionary founders building transformative AI, SaaS, fintech, and enterprise software companies. With a strong track record backing leaders like Dashlane, Guru, and Crossbeam, FirstMark combines deep operational expertise, community-driven founder support, and strategic scaling partnerships to help AI-driven startups reach global markets faster.
Partner Contact: Dan Kozikowski
Email: dan@firstmarkcap.com
Website: www.firstmarkcap.com
LinkedIn: FirstMark Capital
Twitter: @firstmarkcap
Gaingels
Location: New York, USA
Founded: 2015
Fund Type: Angel Network
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, FinTech, Cybersecurity, Developer Tools, Consumer Tech, HealthTech, ClimateTech
Portfolio Highlights: Middesk, GrubMarket, Genies, Yieldstreet, Capchase
Investments: 506
Exits: 17
Description:
Gaingels is a leading angel investment network dedicated to supporting diverse and inclusive leadership teams. They invest across a wide range of industries, with a growing portfolio of AI/ML, SaaS, fintech, and climate tech startups. Gaingels brings a powerful, mission-driven community together with strategic capital, offering founders both funding and an influential network. Their AI/ML-focused investments like Genies and Middesk demonstrate their commitment to future-defining innovation.
Partner Contact: Emilie Poteat
Email: emilie@gaingels.com
Website: www.gaingels.com
LinkedIn: Gaingels
Twitter: @gaingelsvc
Facebook: Gaingels
General Atlantic
Location: New York, USA
Founded: 1980
Fund Type: Venture Fund (Growth Equity)
Fund Stage: Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, FinTech, Cybersecurity, Healthcare, Enterprise Software, CloudTech, EdTech
Portfolio Highlights: Incode Technologies, JumpCloud, Transmit Security, Stellar Health, Devo
Investments: 405
Exits: 138
Description:
General Atlantic is one of the world’s premier growth equity firms, providing capital and strategic guidance to high-growth companies acrossSectors like AI/ML, SaaS, and cybersecurity. Focused on scaling global leaders, General Atlantic supports data-driven companies at later stages who are disrupting industries with transformative AI applications. Notable AI-focused investments include Incode Technologies and Transmit Security, reinforcing their strong footprint in tech-enabled growth.
Partner Contact: Tracey Duff
Email: tduff@generalatlantic.com
Website: www.generalatlantic.com
LinkedIn: General Atlantic
Twitter: @generalatlantic
Facebook: General Atlantic
General Catalyst
Location: New York, USA
Founded: 2000
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, FinTech, Cybersecurity, Healthcare, ClimateTech, E-Commerce, EdTech
Portfolio Highlights: Drift, Fivetran, LatchBio, Aura, Overjet
Investments: 1078
Exits: 172
Description:
General Catalyst is one of the most influential venture capital firms, providing both early-stage and growth-stage funding to companies redefining major industries through AI/ML, data, cybersecurity, and digital health innovations. They support mission-driven founders scaling groundbreaking companies like Drift, Fivetran, and Overjet. With deep operational expertise and global resources, General Catalyst partners from the seed stage all the way through IPO and beyond.
Partner Contact: Jennifer Zimmerman
Email: jzimmerman@generalcatalyst.com
Website: www.generalcatalyst.com
LinkedIn: General Catalyst
Twitter: @gcvp
Facebook: General Catalyst
Golden Seeds
Location: New York, USA
Founded: 2004
Fund Type: Angel Network
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Healthcare, Big Data & Analytics, Mobile, Software, Health & Wellness
Portfolio Highlights: Lark, Gummicube, Modumetal, ZineOne
Investments: 102
Exits: 12
Description:
Golden Seeds is a pioneering early-stage investment firm focused on funding exceptional women-led businesses, while also backing innovation in AI/ML, SaaS, and healthcare. Their mission is to combine strategic capital with mentorship to drive equitable startup growth. With a strong footprint in AI and enterpriseSectors, Golden Seeds supports founders building impactful, scalable technology companies at the critical early stages.
Partner Contact: Lynn Polakoff Baine
Email: lpb@goldenseeds.com
Website: www.goldenseeds.com
LinkedIn: Golden Seeds
Twitter: @GoldenSeeds
Facebook: Golden Seeds
Great Oaks Venture Capital
Location: New York, USA
Founded: 2005
Fund Type: Venture Fund
Fund Stage: Seed, Series A, Series B
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, CloudTech, Healthcare, FinTech, E-Commerce, EdTech, Mobile
Portfolio Highlights: Happy Money, HealthTap, HowGood, UrbanStems, Pocket Gems
Investments: 438
Exits: 102
Description:
Great Oaks Venture Capital is a leading New York-based early-stage venture firm backing tech-driven startups from Seed through Series A. They invest heavily in transformative AI/ML, SaaS, and enterprise technologies, supporting founders who are reimagining industries with innovation and scale. Their diverse portfolio includes standout AI-powered platforms across fintech, edtech, healthtech, and consumer techSectors.
Partner Contact: Henry McNamara
Email: hlmcnamara@greatoaksvc.com
Website: www.greatoaksvc.com
LinkedIn: Great Oaks Venture Capital
Twitter: @GreatOaksVC
Facebook: Great Oaks Venture Capital
Greycroft
Location: New York, USA
Founded: 2006
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, FinTech, Cybersecurity, Developer Tools, CloudTech, E-Commerce, HealthTech
Portfolio Highlights: Immuta, Spectrum Labs, Tapcart, Craft.co, Involve.ai
Investments: 730
Exits: 114
Description:
Greycroft is a top-tier venture capital firm investing in technology startups reshaping industries through innovation. With a strong presence in AI/ML, SaaS, and cloudSectors, Greycroft partners early with founders building the next generation of platforms and marketplaces. Their portfolio spans B2B SaaS, fintech, cybersecurity, healthtech, and enterprise AI, combining deep strategic support with a massive founder network to accelerate company growth.
Partner Contact: John Elton
Email: john@greycroft.com
Website: www.greycroft.com
LinkedIn: Greycroft
Twitter: @greycroftvc
Facebook: Greycroft Partners
HOF Capital
Location: New York, USA
Founded: 2015
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, FinTech, Cybersecurity, Robotics, Healthcare, Mobile
Portfolio Highlights: MoonPay, DuckDuckGo, Figment, Unqork, Flutterwave
Investments: 107
Exits: 3
Description:
HOF Capital is a global multistage venture capital firm with over $1 billion in assets under management, partnering with ambitious entrepreneurs from idea to IPO. Their portfolio includes AI/ML innovators across fintech, cybersecurity, productivity, and enterprise software. HOF’s hands-on approach combines strategic advice, operational resources, and international network access to help AI-driven startups expand globally.
Partner Contact: Victor Wang
Email: vwang@hof.capital
Website: www.hofvc.com
LinkedIn: HOF Capital
Twitter: @HOFCapital
IA Ventures
Location: New York, USA
Founded: 2010
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, FinTech, SaaS, Cybersecurity, Healthcare, Information Technology
Portfolio Highlights: Octane, Recorded Future, YipitData, PlaceIQ, Komodo Health
Investments: 146
Exits: 28
Description:
IA Ventures is a highly focused seed and early-stage venture capital firm based in New York, backing companies that build competitive advantages through AI/ML, data, and fintech innovation. Known for deep technical support and a strong founder-first philosophy, IA Ventures partners with startups pushing the limits of predictive analytics, cybersecurity, and healthcare intelligence.
Partner Contact: Jesse Beyroutey
Email: jesse@iaventures.com
Website: www.iaventures.com
LinkedIn: IA Ventures
Twitter: @iaventures
Facebook: IA Ventures
Insight Partners
Location: New York, USA
Founded: 1995
Fund Type: Venture Fund (Growth Equity & Private Equity)
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, FinTech, CloudTech, Healthcare, Cybersecurity, PropTech, E-Commerce
Portfolio Highlights: Dataiku, LaunchDarkly, CertiK, MURAL, PlanetScale
Investments: 910
Exits: 185
Description:
Insight Partners is one of the world's most prominent growth equity firms, investing across the software, internet, and AI/ML landscape. Focused on scaling high-potential companies globally, Insight backs founders building the next generation of enterprise software, SaaS platforms, cybersecurity solutions, and AI-powered applications. Their track record includes major AI-driven success stories like Dataiku, CertiK, and LaunchDarkly.
Partner Contact: Jeffrey L. Horing
Email: jeffrey.horing@ncino.com
Website: www.insightpartners.com
LinkedIn: Insight Partners
Twitter: @insightpartners
Facebook: Insight Venture Partners
Invus
Location: New York, USA
Founded: 1985
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), BioTech, Healthcare, Life Sciences, FinTech, Food & Beverage
Portfolio Highlights: KSQ Therapeutics, Element Science, Engine Biosciences, Imvax, Cava Group
Investments: 163
Exits: 49
Description:
Invus is a global investment firm that takes a flexible, tailored approach to building exceptional companies. With deep expertise across AI/ML, biotechnology, healthcare innovation, and fintech, Invus focuses on long-term partnerships with visionary founders. Their investments blend AI with transformational advancements in healthcare and life sciences, pushing boundaries in precision medicine, drug discovery, and wearable technology.
Partner Contact: Benjamin Tsai
Email: bt@invus.com
Website: www.invus.com
LinkedIn: Invus
JP Morgan Chase
Location: New York, USA
Founded: 2000
Fund Type: Corporate Venture Capital (CVC)
Fund Stage: Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Big Data & Analytics, Cybersecurity, CloudTech, FinTech, Healthcare, Mobile, Enterprise
Portfolio Highlights: Grafana Labs, Airtable, Plaid, Kensho, ReversingLabs
Investments: 173
Exits: 58
Description:
JP Morgan Chase’s Corporate VC arm strategically invests in disruptive AI/ML startups and technology innovators reshaping the financial services landscape. Backing companies in AI-driven cybersecurity, enterprise SaaS, data infrastructure, and fintech, JP Morgan leverages its deep industry experience to help portfolio companies scale globally and connect to major markets.
Partner Contact: Beth Rockwell
Email: beth.r.rockwell@jpmchase.com
Website: www.jpmorganchase.com
LinkedIn: JP Morgan Chase
Twitter: @jpmorgan
Facebook: JP Morgan Chase
Lux Capital
Location: New York, USA
Founded: 2000
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, Healthcare, Robotics, DeepTech, BioTech, CloudTech, SpaceTech, Cybersecurity, SaaS
Portfolio Highlights: Hugging Face, Primer, Covariant, Sourcegraph, Tecton
Investments: 403
Exits: 47
Description:
Lux Capital is a premier venture capital firm investing in visionary founders at the intersection of science and technology. Deeply committed to AI/ML innovation, Lux backs companies inSectors like healthcare AI, autonomous robotics, advanced analytics, and frontier technologies. Their investments into companies like Hugging Face and Covariant underline their belief in the transformative power of artificial intelligence on global industries.
Partner Contact: Adam Goulburn
Email: adam.goulburn@luxcapital.com
Website: www.luxcapital.com
LinkedIn: Lux Capital
Twitter: @Lux_Capital
Facebook: Lux Capital
NextView Ventures
Location: New York, USA
Founded: 2010
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Marketplace, Big Data & Analytics, CloudTech, Developer Tools, Healthcare, FinTech, RetailTech
Portfolio Highlights: Drift, Reforge, Grove Collaborative, Dia&Co, Optimus Ride
Investments: 208
Exits: 37
Description:
NextView Ventures is a seed-stage VC firm with a mission to invest in companies shaping a brighter collective future. With a strong emphasis on AI/ML-enabled startups, they back bold founders building transformative SaaS tools, smart marketplaces, and cutting-edge tech products. NextView’s hands-on approach and operational support have made it a trusted partner for emerging AI companies.
Partner Contact: Rob Go
Email: rob@nextviewventures.com
Website: www.nextviewventures.com
LinkedIn: NextView Ventures
Twitter: @NextViewVC
Operator Partners
Location: New York, USA
Founded: 2020
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, CloudTech, Big Data & Analytics, Developer Tools, FinTech, Healthcare, Cybersecurity, Information Technology
Portfolio Highlights: Spring Health, Vendia, Material Security, Indigov, Stytch
Investments: 120
Exits: 2
Description:
Operator Partners is an early-stage venture firm founded by seasoned operators who back technical and visionary entrepreneurs. With a strong focus on AI/ML innovations, they invest across enterprise SaaS, developer tools, healthcare AI, and next-gen cloud and cybersecurity startups. Their operator-first approach ensures founders get not just capital but deep, tactical support during their early growth stages.
Partner Contact: Olivia Benjamin
Email: olivia@operatorpartners.com
Website: www.operatorpartners.com
LinkedIn: Operator Partners
Twitter: No official Twitter listed
OrbiMed
Location: New York, USA
Founded: 1989
Fund Type: Venture Fund
Fund Stage: Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), BioTech, Healthcare, Life Sciences, Medical Devices, Pharmaceuticals, Health & Wellness, FemTech, HR Tech, Software
Portfolio Highlights: Aspen Neuroscience, Carrot Fertility, Sionna Therapeutics, XtalPi, Odyssey Therapeutics
Investments: 562
Exits: 212
Description:
OrbiMed is one of the world’s largest dedicated healthcare investment firms. They back innovative companies across biopharma, AI-driven life sciences, healthcare IT, and medical devices. With decades of experience, OrbiMed provides not just capital but also strategic expertise to founders revolutionizing the intersection of health, technology, and artificial intelligence.
Partner Contact: Carl Gordon
Email: gordonc@orbimed.com
Website: www.orbimed.com
LinkedIn: OrbiMed Advisors
Twitter: @OrbiMed
Point72 Ventures
Location: New York, USA
Founded: 2016
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), FinTech, Deep Tech, Cybersecurity, Big Data & Analytics, Robotics, SaaS, BioTech, Healthcare, E-Commerce, Developer Tools, Information Technology, and more.
Portfolio Highlights: Shield AI, Stellar Health, Deep 6 AI, NetraDyne, Fauna
Investments: 128
Exits: 11
Description:
Point72 Ventures is a global venture capital firm backed by billionaire investor Steven A. Cohen. The firm partners early with entrepreneurs building disruptive companies across fintech, deep tech, AI/ML, cybersecurity, and enterpriseSectors. Their approach combines patient capital with operational expertise to help visionary founders accelerate their impact on global industries.
Partner Contact: Daniel Gwak
Email: daniel.gwak@point72ventures.com
Website: www.p72.vc
LinkedIn: Point72 Ventures
Twitter: @p72vc
R/GA Ventures
Location: New York, USA
Founded: 2013
Fund Type: Corporate Venture Capital
Fund Stage: Seed, Series A, Series B
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, SaaS, PropTech, IoT (Internet of Things), Software, Mobile, Advertising (AdTech), Marketing (MarTech), Healthcare, Entertainment & Media, ClimateTech & CleanTech, and more.
Portfolio Highlights: Enertiv, Lytics, Cordial, Swish Analytics, PetPlate
Investments: 124
Exits: 16
Description:
R/GA Ventures is the investment arm of the global innovation consultancy R/GA. They specialize in helping industry leaders capitalize on disruptive technologies by investing in startups reshapingSectors like AI/ML, SaaS, IoT, and more. Beyond capital, they offer strategic resources, corporate partnerships, and hands-on operational support to help companies accelerate growth.
Partner Contact: Jonathan Bradley
Email: jonathan.bradley@rga.com
Website: ventures.rga.com
LinkedIn: R/GA Ventures
Twitter: @rgaventures
RRE Ventures
Location: New York, USA
Founded: 1994
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, FinTech, Software, Healthcare, Cryptocurrency / Blockchain, Apps, IoT (Internet of Things), PropTech, Robotics, RetailTech, Developer Tools, and more.
Portfolio Highlights: YipitData, Securrency, Braintree, Groups Recover Together, Branch
Investments: 584
Exits: 120
Description:
RRE Ventures is one of New York's original venture capital firms, backing extraordinary entrepreneurs since 1994. They invest across a broad range of disruptiveSectors with a strong focus on AI/ML, FinTech, enterprise software, and emerging technologies. RRE supports founders from seed to growth stages with capital, mentorship, and strategic guidance.
Partner Contact: Will Porteous
Email: will@rre.com
Website: www.rre.com
LinkedIn: RRE Ventures
Twitter: @rre
StartUp Health
Location: New York, USA
Founded: 2011
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Healthcare, Health & Wellness, Elder Care, Mobile, FinTech, Enterprise, Developer Tools, Big Data & Analytics, EdTech, Life Science, and BioTech.
Portfolio Highlights: Devoted Health, Fruit Street, Babyscripts, MedHaul, Particle Health, Cala Health
Investments: 340
Exits: 26
Description:
StartUp Health is a mission-driven venture firm investing in a global "army of Health Transformers" — entrepreneurs dedicated to improving health and wellness worldwide. They focus heavily on innovations driven by AI/ML across digital health, life sciences, wellness, and elder careSectors, nurturing companies at the intersection of healthcare and technology.
Partner Contact: Steven Krein
Email: steve@startuphealth.com
Website: www.startuphealth.com
LinkedIn: StartUp Health
Twitter: @StartUpHealth
Stripes
Location: New York, USA
Founded: 2008
Fund Type: Venture Fund
Fund Stage: Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Health & Wellness, Healthcare, Big Data & Analytics, Information Technology, HR Tech, Enterprise, FinTech, SaaS, Software, E-Commerce, Consumer Goods, Cybersecurity, and more.
Portfolio Highlights: Hello Heart, Replicant, Verbit, Paradox, Dataiku, Novo, FullStory, Lithic, Settle, Island
Investments: 110
Exits: 21
Description:
Stripes is a growth equity firm that backs forward-thinking software and consumer businesses. They actively invest in AI/ML-driven startups transforming industries like healthcare, enterprise SaaS, and e-commerce. Stripes combines deepSector expertise with a flexible investment approach to accelerate company growth from early stages to scale.
Partner Contact: Jason Santiago
Email: jason@stripesgroup.com
Website: www.stripes.co
LinkedIn: Stripes
Twitter: @stripesco_
The Fund
Location: New York, USA
Founded: 2018
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), FinTech, SaaS, PropTech, Big Data & Analytics, Developer Tools, CloudTech, Consumer Internet, DeepTech, Healthcare, and more.
Portfolio Highlights: DEV, Lalo, StayTuned, Huckleberry Labs
Investments: 179
Exits: 4
Description:
The Fund is a community-powered venture firm comprised of successful founders and operators who invest in the next generation of startups. They emphasize investing early in bold entrepreneurs building AI, SaaS, and next-gen tech companies across diverse industries. With strong operator support and real-world insights, The Fund helps startups scale faster and smarter.
Partner Contact: Jenny Fielding
Email: jenny@thefund.vc
Website: www.thefund.vc
LinkedIn: The Fund
Twitter: @TheFundGlobal
Third Kind Venture Capital
Location: New York, USA
Founded: 2010
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, Healthcare, ClimateTech & CleanTech, FinTech, E-Commerce, Robotics, BioTech, Health & Wellness, Software, EdTech, and more.
Portfolio Highlights: HowGood, Recurate, Lemonaid Health, Hopscotch, Pickle Robot, Envisagenics, TryNow, Hero Health
Investments: 124
Exits: 20
Description:
Third Kind Venture Capital (3KVC) focuses on early-stage investments across a wide range of technologySectors, with a strong emphasis on AI/ML-driven innovation. They back companies at the intersection of cutting-edge technology and large market opportunities, helping founders with critical early funding and guidance to reach product-market fit and scale rapidly.
Partner Contact: Alex Binkley
Email: alex@3kvc.com
Website: www.3kvc.com
Thrive Capital
Location: New York, USA
Founded: 2009
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, FinTech, Big Data & Analytics, Healthcare, HR Tech, E-Commerce, CloudTech, Mobile, Enterprise, Information Technology, Advertising (AdTech), Marketing (MarTech), RetailTech, Entertainment & Media, Sports, B2B, Consumer Goods, Fashion, Cannabis, EdTech, Consulting, and more
Portfolio Highlights:
Nava, LeafLink, Skims, Grailed, CommandBar, Sailthru, Scope Security, Imprint, Parafin, Otter, Mojo, Heir
Investments: 302
Exits: 63
Description:
Thrive Capital is a leading New York-based venture capital investment firm focused on building and backing transformative software and technology-enabled companies. With a strong emphasis on innovation, particularly in AI/ML, SaaS, FinTech, and HealthTech, Thrive Capital partners with visionary founders shaping the future of industries.
Partner Contact: Nabil Mallick
Email: nabil@thrivecap.com
Website: www.thrivecap.com
Tribeca Venture Partners
Location: New York, USA
Founded: 2011
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus:
Artificial Intelligence & Machine Learning (AI/ML), SaaS, FinTech, Big Data & Analytics, Software, Healthcare, Cryptocurrency / Blockchain, Developer Tools, Information Technology, Enterprise Solutions, EdTech, Health & Wellness, PropTech, ClimateTech & CleanTech, Robotics, Construction Tech, Collaboration Tools, Advanced Materials, Travel, Outdoors, Events, and more
Portfolio Highlights:
Zebedee, Vivvi, Thinkful, Tentrr, Quantum Circuits, Crafty, AiCure, Lendio, Hive, Truveris, Toggle, Actuate
Investments: 118
Exits: 16
Description:
Tribeca Venture Partners (TVP) is an early-stage venture capital firm based in New York City, investing in innovative companies at the intersection of technology and real-world impact. With strong roots inSectors like SaaS, AI/ML, FinTech, and HealthTech, TVP actively supports digital-first entrepreneurs building groundbreaking solutions for the future.
Partner Contact: Brian Hirsch
Email: brian@tribecavp.com
Website: www.tribecavp.com
Two Sigma Ventures
Location: New York, USA
Founded: 2012
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Big Data & Analytics, FinTech, Healthcare, Life Science, PropTech, Infrastructure, Manufacturing, Telecommunications (TMT)
Portfolio Highlights:
Bark Technologies, Timescale, Wristcam, Replicated, Boundless, NewtonX, Lytics, Indico Data, Kasisto, CoverWallet, Enveda Biosciences, Xilis, Hexagon Bio, and many more.
Investments: 180
Exits: 21
Description:
Two Sigma Ventures is an early-stage venture capital fund backed by the scientific mindset of Two Sigma. They invest in data-driven companies across AI, fintech, healthcare, life sciences, and infrastructure, partnering with mission-driven founders building transformative technology businesses.
Partner Contact: Colin Beirne
Email: colin@twosigmaventures.com
Website: www.twosigmaventures.com
Union Square Ventures (USV)
Location: New York, USA
Founded: 2003
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A, Series B, Series C, Series D
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Privacy, Software, E-Commerce, FinTech, EdTech, Logistics, Transportation, Health & Wellness, Healthcare, Big Data & Analytics, Information Technology, Marketing (MarTech), InsurTech, Developer Tools, Community, Enterprise, Cybersecurity, PropTech, Professional Services, IoT (Internet of Things), Cryptocurrency / Blockchain, ClimateTech & CleanTech, Robotics
Portfolio Highlights:
DuckDuckGo, Dia&Co, Quizlet, SmartHop, CoverWallet, Yieldmo, Sofar Ocean, Slope, Bolster, Veniam, Alife, Brave Health, Simulmedia, Stack Exchange, Recount Media, and many more.
Investments: 392
Exits: 54
Description:
Union Square Ventures is a thesis-driven venture capital firm backing trusted brands that broaden access to knowledge, capital, and well-being. USV focuses on early-stage and growth investments in transformational industries like AI, blockchain, privacy tech, fintech, and healthcare.
Partner Contact: Albert Wenger
Email: albert@usv.com
Website: www.usv.com
White Star Capital
Location: New York, USA
Founded: 2007
Fund Type: Venture Fund
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), FinTech, InsurTech
PropTech, Healthcare, Medical Device, Enterprise, Hardware, Apps, RetailTech, Robotics, Augmented & Virtual Reality (AR/VR), Software, E-Sports (Gaming), Creator Economy, Information Technology
Portfolio Highlights:
TheGuarantors, Parsley Health, KeyMe, Spatial, Sizzle, Percent
Investments: 133
Exits: 15
Description:
White Star Capital is an international venture capital and early growth-stage investment firm focused on backing ambitious entrepreneurs building enduring technology businesses acrossSectors like AI, healthcare, fintech, proptech, and more.
Partner Contact: Nick Stocks
Email: nick@whitestarvc.com
Website: www.whitestarcapital.com
Winklevoss Capital
Location: New York, USA
Founded: 2012
Fund Type: Family Office
Fund Stage: Seed, Series A, Series B
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), SaaS, Healthcare, Software, E-Commerce, RetailTech, Big Data & Analytics, Developer Tools, FinTech, PropTech, Information Technology, ClimateTech & CleanTech, Delivery, Marketplace, Hospitality, Transportation, Health & Wellness, Robotics, EdTech, Consumer Goods, Fashion, Food and Beverage, Advertising (AdTech), Marketing (MarTech), CRM
Portfolio Highlights:
Eaze, Narrativ, Caviar, Triplemint, Hydrow, Matternet, Teachable, MeUndies, Onfleet, Compology
Investments: 136
Exits: 28
Description:
Winklevoss Capital is a family office investing in determined entrepreneurs, championing innovation across AI/ML, SaaS, healthcare, fintech, consumer tech, and more. Their philosophy centers on enabling founders to build a frictionless world.
Partner Contact: Sterling Witzke
Email: sterling@winklevosscapital.com
Website: www.winklevosscapital.com
XRC Labs
Location: New York, USA
Founded: 2015
Fund Type: Accelerator
Fund Stage: Pre-Seed, Seed, Series A
Sector Focus: Artificial Intelligence & Machine Learning (AI/ML), Healthcare, Health & Wellness, RetailTech, E-Commerce, Consumer Goods, Enterprise, Software, Sales Automation, Medical Device, Food and Beverage, FinTech, Mobile, Marketplace, Beauty, Logistics, B2B, Apps, Supply Chain Tech, Robotics, Consumer
Portfolio Highlights:
Snappy, Recurate, Billie, Ash Wellness, Gather AI, OrthoFX, Boost, Swivel, Pod Foods Co
Investments: 114
Exits: 8
Description:
XRC Labs is an innovation accelerator fueling the next generation of disruptors across retail tech, consumer goods, healthcare, AI, and logistics. Their focus is on scaling startups that redefine consumer experiences and enterprise efficiencies.
Partner Contact: Diana Melencio
Email: diana@xrclabs.com
Website: www.xrclabs.com
Why You Should Care
AI and machine learning are among the fastest growingSectors today. Investors are aggressively backing startups that apply AI to fields like healthcare, SaaS, fintech, edtech, cybersecurity, and beyond.
By knowing which VCs actively invest in your space, you can tailor your pitch decks, personalize your outreach, and significantly increase your chances of securing funding.
And speaking of increasing your chances...
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Conclusion
Fundraising for your AI startup doesn't have to feel like shooting arrows in the dark.
Use this curated list of New York's top venture firms, do your research, personalize your approach, and most importantly — secure your sensitive documents properly.
Good luck with your raise!
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